The article, “ASPSCR1::TFE3 orchestrates the angiogenic program of alveolar soft part sarcoma”, investigates alveolar soft part sarcoma (ASPS) and its prominent angiogenic activity, focusing on the role of the fusion transcription factor ASPSCR1::TFE3 in tumor development and angiogenesis. The study reveals that ASPSCR1::TFE3 is required for in vivo tumor development (using PrimeSurface 96U MS-9096UZ) through angiogenesis, as it influences super-enhancer activity and regulates critical targets involved in the construction of the ASPS vascular network.

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