The article, published in Nature Scientific Reports by the Seoul National University College of Medicine, investigates the role of hypoxia-inducible factor-1α (HIF-1α) in hair follicle development using PrimeSurface 96U (MS-9096UZ) and regeneration in androgenetic alopecia patients. The study reveals that HIF-1α is suppressed in scalp tissues of these patients and demonstrates that activating HIF-1α can elevate the expression of trichogenic genes, suggesting its potential as a therapeutic target and tissue engineering approach for hair loss treatment.
Hypoxia inducible factor-1α promotes trichogenic gene expression in human dermal papilla cells
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