3D Cell Culture

S-BIO’s 3D Cell Culture products are used for stem cell research, drug discovery & development, tissue engineering & regenerative medicine.

  • Ultra Low Attachment (ULA) Plates
  • Spheroid White Plates
  • Well Plates
  • Form Uniform Spheroids with Ultra-low Attachment PrimeSurface® Cell Culture Plate

    PrimeSurface® cultureware are ultra low attachment (ULA) dishes and plates that promote scaffold free, self assembly of spheroid formation. The plates are pre-coated with unique ultra hydrophilic polymer that enables spontaneous spheroid formation of uniform size and shape.   The ULA plates have high optical clarity making them highly suitable for bright field imaging and confocal microscopy.  In addition to the widely used 96 well U bottom plate, 96 well plates are also available in V and M bottom, giving scientists a choice to form tighter spheroids that are needed for specific cell types.  For high throughput screening (HTS) needs,  384 well plates are available in clear and white.
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    Ideal for Luminescent Assays

    White plates are the best choice for luminescence.  Using PrimeSurface® 96 and 384 well ULA white plates, cancer spheroid cells can be formed and analyzed in the same multiwell plate for luminescence assays. This streamlined process reduces the experimental steps and time required in drug testing, furthermore prevents spheroid damage and provides a robust, high sensitivity assay for luminescent based high throughput screening.    
  • A new design of ultra-low attachment 3D plate to facilitate easy handling of media exchange without disrupting spheroid formation. Enhanced Stem Cell Culturing in Regenerative Medicine Cell culturing involves frequent media replacement to provide nutrition to growing cells. In a standard 96 well ultra low cell attachment plate, media aspiration or dispensing has to be done extremely carefully to avoid disturbing the unattached spheroid, making this a time consuming operation. With the introduction of PrimeSurface® 96 Slit-well Plate, media exchange for 96 well plates can be efciently handled with one step dispensing or aspiration for all 96 wells decreasing the pipetting time by over 80% while minimizing the risk of spheroid damage.