A novel type of mesoporous silica-based nanoparticle (BSH-BPMO) containing covalently attached boron-10, a crucial component for boron neutron capture therapy (BNCT) that is conducted by Kyoto University. The nanoparticles efficiently enhance boron internalization in cancer cells, leading to improved BNCT efficacy compared to the commonly used drugs BSH and BPA in clinical trials. Note: spheroids were created using ultra low attachment plates PrimeSurface 96U (MS-9096UZ).

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